A three-year starter at strong safety for Clemson University, Dawkins was chosen in the second round of the 1996 NFL Draft by the Philadelphia Eagles.

In 2008, Dawkins was named "Father of the Year" by the American Diabetes Association for his dedication to his family and community. Dawkins has also made generous contributions of $50,000 and $100,000 to Forest View Pop Warner and William M. Raines High School in Jacksonville, where he started his football career.

On April 23, 2012, Dawkins announced his retirement after 16 NFL seasons.

A nine-time Pro Bowl selection, Dawkins is a member of the Philadelphia Eagles 75th Anniversary Team, the NFL 2000s All-Decade Team and the 20/20 Club (20 sacks, 20 interceptions).