Amani Toomer attended the University of Michigan. As a junior in 1994, he became only the third player in school history, after Jack Clancy and Desmond Howard, to post 1,000 receiving yards in a season, finishing with 54 receptions for 1,096 yards and six touchdowns; he was named to the All-Big Ten Conference First Team. His senior year in 1995, Toomer caught 44 passes for 758 yards and seven scores and was voted to the All-Big Ten Second Team.

He was drafted by the New York Giants in the second round of the 1996 NFL Draft. He played for the Giants from 1996-2008. He was the starting wide receiver for the Super Bowl Champion Giants in Super Bowl XLII.

Amani Toomer's career highlights and awards include: USA Today High School All-American (1991), First-team All-Big Ten (1994), Super Bowl Champion (XLII), and New York Giants Ring of Honor. He finished his career with 668 receptions, 9,497 receiving yards and 54 receiving touchdowns.