Strahan attended Texas Southern University and was drafted in the second round of the 1993 NFL Draft by the New York Giants. He has held the NFL record for sacks in a single season with 22.5, breaking Mark Gastineau's total of 22 in the 2001 season. In 2001 and 2003, Strahan was named the NFL Defensive Player of the Year.  He is a seven time Pro-Bowl selection and a four time First-Team All-Pro selection.

After helping to upset the Patriots in Super Bowl XLII, Strahan retired from the NFL. He finishd his career with 141.5 sacks, 794 tackles, 4 interceptions, 21 forced fumbles in 200 games over a 15 year career. 

Strahan has appeared and played golf in an advertisement for Right Guard, appeared in a Snickers commercial, and appeared in a Subway Restaurants commercial with Jared Fogle. He was also on the cover of the final videogame of the NFL Blitz series.