James Jones attended American Senior High in Miami was picked 49th by the Indiana Pacers in the 2003 NBA Draft out of the University of Miami. Jones was traded by the Pacers to the Phoenix Suns on August 25, 2005. In June 2007, Jones was traded to the Portland Trail Blazers. On July 9, 2008, Jones signed a contract with the Miami Heat.
On February 19, 2011, Jones won the Three-Point Shootout in Los Angeles at the Staples Center. In the following year, an impressive playoff run by the Heat culminated in Jones' first ever NBA championship, and the franchise's second. On December 9, 2011, Jones was re-signed by the Miami Heat for $4.5 million over 3 years.